1608—Gravedona, Italy

Glory of God the Father and the Angels, a fresco by Giovanni Mauro della Rovere (also known as Fiammenghino), located in the Church of Santi Gusmeo e Matteo, includes a depiction of what could be a trombone. The instrument has characteristics of both slide trumpet and trombone; it could simply be an awkwardly-rendered depiction of either instrument. Other nearby angel-musicians play viol, organ, flute, and lute (see detail and full image below; public domain) (Angelis 43).

Fiammenghino detail

Fiammenghino medium